The weekend effect in kidney transplantation outcomes: a French cohort‐based study

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Ville, Simon | Branchereau, Julien | Cornuaud, Adeline | Dantal, Jacques | Legendre, Christophe | Buron, Fanny | Morelon, Emmanuel | Garrigue, Valérie | Lequentrec, Moglie | Albano, Laetitia | Cassuto, Elisabeth | Girerd, Sophie | Ladrière, Marc | Glotz, Denis | Lefaucher, Carmen | Kerleau, Clarisse | Foucher, Yohann | Giral, Magali

Edité par CCSD ; Frontiers Media -

International audience. Background: Numerous studies have reported a weekend effect on outcomes for diseases treated at hospitals. No study has been conducted in France for kidney transplantation. We therefore performed a cohort-based study to evaluate whether outcomes of kidney transplant recipients display a weekend effect.Methods: Data were extracted from the French DIVAT cohort. Patients aged 18 years and older, transplanted with a single kidney from deceased donors between 2005 and 2017 were studied. Linear regression, logistic regression and cause specific Cox model were used.Results: Among the 6652 studied patients, 4653 patients were transplanted during weekdays (69.9%) versus 1999 during weekends (30.1%). The only statistically significant difference was the percentage of patients with vascular surgical complication(s) at 30 days: 13.3% in the weekend group versus 16.2% in the weekday group 0.79 (95% CI: 0.68; 0.92). We did not observe other significant differences for the other outcomes: patient or graft survival, the risk of acute rejection episodes, the 30-day percentage of urological complications, and the 1-year estimated glomerular filtration rate.Conclusion: Our study highlights a small protective weekend effect with less post-surgery vascular complications compared to weekdays. This paradox might be explained by a different handling of weekend transplantations.

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