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Tailored Control and Optimisation of the Number of Phosphonic Acid Termini on Phosphorus-Containing Dendrimers for the Ex-Vivo Activation of Human Monocytes

Archive ouverte | Rolland, Olivier | CCSD

International audience. The syntheses of a series of phosphonic acid-capped dendrimers is described. This collection is based on a unique set of dendritic structural parameters-cyclo(triphosphazene) core, benzylhydr...

Design of phosphorylated dendritic architectures to promote human monocyte activation

Archive ouverte | Poupot, Mary | CCSD

International audience. As first defensive line, monocytes are a pivotal cell population of innate immunity. Monocyte activation can be relevant to a range of immune conditions and responses. Here we present new ins...

Dendrimers ended by non-symmetrical azadiphosphonate groups: Synthesis and immunological properties

Archive ouverte | Marchand, Patrice | CCSD

International audience. The synthesis and characterization of new series of phosphorus-containing dendrimers ended by non-symmetrical azamonophosphonates, or azadiphosphonates, or azadiphosphonic acid salts are repo...

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