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CX3CR1 regulates gut microbiota and metabolism. A risk factor of type 2 diabetes

Archive ouverte | Pomié, Celine | CCSD

International audience. Objective: The intestinal microbiota to immune system crosstalk is a major regulator of metabolism and hence metabolic diseases. An impairment of the chemokine receptor CX3CR1, as a key regul...

Periodontitis induced by Porphyromonas gingivalis drives periodontal microbiota dysbiosis and insulin resistance via an impaired adaptive immune response

Archive ouverte | Blasco-Baque, Vincent | CCSD

International audience. OBJECTIVE: To identify a causal mechanism responsible for the enhancement of insulin resistance and hyperglycaemia following periodontitis in mice fed a fat-enriched diet. DESIGN: We set-up a...

Liraglutide targets the gut microbiota and the intestinal immune system to regulate insulin secretion

Archive ouverte | Charpentier, Julie | CCSD

International audience. Aims: Liraglutide controls type 2 diabetes (T2D) and inflammation. Gut microbiota regulates the immune system and causes at least in part type 2 diabetes. We here evaluated whether liraglutid...

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