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Highly sensitive methods are required to detect mutations in histiocytoses

Archive ouverte | Melloul, Sarah | CCSD

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Archive ouverte | Durham, Benjamin | CCSD

International audience. Langerhans cell histiocytosis (LCH) and the non-LCH neoplasm Erdheim-Chester disease (ECD) are heterogeneous neoplastic disorders marked by infiltration of pathologic macrophage-, dendritic c...

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Archive ouverte | Héritier, Sébastien | CCSD

International audience. Neurodegenerative (ND) complications in Langerhans cell histiocytosis (LCH) are a late-onset but dramatic sequelae for which incidence and risk factors are not well defined. Based on a nation...

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