Afficher la couverture 'Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy | Ghossoub, Rania' en grand format
/5

0 avis

Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy

Archive ouverte

Ghossoub, Rania | Lindbæk, Louise | Mollà-Herman, Anahi | Schmitt, Alain | Christensen, Søren Tvorup | Benmerah, Alexandre

Edité par CCSD -

International audience. In many vertebrate cell types, the proximal part of the primary cilium is positioned within an invagination of the plasma membrane known as the ciliary pocket. Recent evidence points to the conclusion that the ciliary pocket comprises a unique site for exocytosis and endocytosis of ciliary proteins, which regulates the spatiotemporal trafficking of receptors into and out of the cilium to control its sensory function. In this chapter, we provide methods based on electron microscopy, 3D reconstruction of fluorescence images as well as live cell imaging suitable for investigating processes associated with endocytosis at the ciliary pocket.

Suggestions

Du même auteur

Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy

Archive ouverte | Ghossoub, Rania | CCSD

International audience. In many vertebrate cell types, the proximal part of the primary cilium is positioned within an invagination of the plasma membrane known as the ciliary pocket. Recent evidence points to the c...

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

Archive ouverte | Ghossoub, Rania | CCSD

International audience. The primary cilium (PC) is present on most cell types in both developing and adult tissues in vertebrates. Despite multiple reports in the sixties, the PC was almost forgotten for decades by ...

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

Archive ouverte | Mollà-Herman, Anahi | CCSD

International audience. Cilia and flagella are eukaryotic organelles involved in multiple cellular functions. The primary cilium is generally non motile and found in numerous vertebrate cell types where it controls ...

Chargement des enrichissements...