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Alpha interferon restricts human T-lymphotropic virus type 1 and 2 de novo infection through PKR activation.

Archive ouverte | Cachat, Anne | CCSD

International audience. Type I interferon (IFN-I) inhibits the replication of different viruses. However, the effect of IFN-I on the human T-lymphotropic virus type 1 (HTLV-1) viral cycle is controversial. Here, we ...

ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity.

Archive ouverte | Cachat, Anne | CCSD

Affiliations ECOFECT. International audience. The role of innate immunity in general and of type I interferon (IFN-I) in particular in HTLV-1 pathogenesis is still a matter of debate. ADAR1-p150 is an Interferon Sti...

Double-stranded RNA adenosine deaminase ADAR1 enhances both T cell susceptibility to human T-cell leukemia virus type 1 and 2 and viral replication

Archive ouverte | Cachat, Anne | CCSD

International audience

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