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Air-liquid interface exposure to aerosols of poorly soluble nanomaterials induces different biological activation levels compared to exposure to suspensions

Archive ouverte | Loret, Thomas | CCSD

International audience. Background : Recently, much progress has been made to develop more physiologic in vitro models of the respiratory system and improve in vitro simulation of particle exposure through inhalatio...

Predicting toxic effects observed in vivo after acute exposure to poorly soluble and inhalable nanomaterials by using more complex in vitro models

Archive ouverte | Loret, Thomas | CCSD

International audience. Animal models are powerful tools to predict potential adverse effects in human after inhalation of Nanomaterials (NM), because of similar levels of complexity. Nevertheless, considering the n...

The Use of sp-ICP-MS to Study the Behavior of Inhaled TiO2 NPs in Lung's Compartments

Archive ouverte | Ben Dhiab, Ibtihel | CCSD

International audience. The purpose of the work was to assess the contribution of sp-ICP-MS for nanoparticle (NP) biodistribution studies, with the exemple of inhaled TiO2 NPs fate in rat lungs.

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