Causal and Associational Language in Observational Health Research: A Systematic Evaluation

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Haber, Noah | Wieten, Sarah | Rohrer, Julia | Arah, Onyebuchi | Tennant, Peter | Stuart, Elizabeth | Murray, Eleanor | Pilleron, Sophie | Lam, Sze Tung | Riederer, Emily | Howcutt, Sarah Jane | Simmons, Alison | Leyrat, Clémence | Schoenegger, Philipp | Booman, Anna | Dufour, Mi-Suk Kang | O’donoghue, Ashley | Baglini, Rebekah | Do, Stefanie | Takashima, Mari de la Rosa | Evans, Thomas Rhys | Rodriguez-Molina, Daloha | Alsalti, Taym | Dunleavy, Daniel | Meyerowitz-Katz, Gideon | Antonietti, Alberto | Calvache, Jose | Kelson, Mark | Salvia, Meg | Parra, Camila Olarte | Khalatbari-Soltani, Saman | Mclinden, Taylor | Chatton, Arthur | Seiler, Jessie | Steriu, Andreea | Alshihayb, Talal | Twardowski, Sarah | Dabravolskaj, Julia | Au, Eric | Hoopsick, Rachel | Suresh, Shashank | Judd, Nicholas | Peña, Sebastián | Axfors, Cathrine | Khan, Palwasha | Rivera Aguirre, Ariadne | Odo, Nnaemeka | Schmid, Ian | Fox, Matthew

Edité par CCSD ; Oxford University Press (OUP) -

International audience. Abstract We estimated the degree to which language used in the high-profile medical/public health/epidemiology literature implied causality using language linking exposures to outcomes and action recommendations; examined disconnects between language and recommendations; identified the most common linking phrases; and estimated how strongly linking phrases imply causality. We searched for and screened 1,170 articles from 18 high-profile journals (65 per journal) published from 2010–2019. Based on written framing and systematic guidance, 3 reviewers rated the degree of causality implied in abstracts and full text for exposure/outcome linking language and action recommendations. Reviewers rated the causal implication of exposure/outcome linking language as none (no causal implication) in 13.8%, weak in 34.2%, moderate in 33.2%, and strong in 18.7% of abstracts. The implied causality of action recommendations was higher than the implied causality of linking sentences for 44.5% or commensurate for 40.3% of articles. The most common linking word in abstracts was “associate” (45.7%). Reviewers’ ratings of linking word roots were highly heterogeneous; over half of reviewers rated “association” as having at least some causal implication. This research undercuts the assumption that avoiding “causal” words leads to clarity of interpretation in medical research.

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