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LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

Archive ouverte | Radu, Anca | CCSD

International audience. Metabolic processes underlying the development of the neural crest, an embryonic population of multipotent migratory cells, are poorly understood. Here, we report that conditional ablation of...

Preventing neuropathy and improving anti-cancer chemotherapy with a carbazole-based compound

Archive ouverte | Bosc, Lauriane | CCSD

International audience. Abstract Advances in cancer treatment have led to a steady increase in the rate of disease remission. However, while many treatment-related adverse effects gradually resolve after therapy, ch...

Functions of LKB1 in neural crest development: The story unfolds

Archive ouverte | Thibert, Chantal | CCSD

International audience. Neural crest cells (NCCs) are highly motile, multipotent, embryonic cells that delaminate from the dorsal edges of the neural tube. NCCs follow stereotypical long-range migratory pathways to ...

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