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MicroRNAs Establish Robustness and Adaptability of a Critical Gene Network to Regulate Progenitor Fate Decisions during Cortical Neurogenesis

Archive ouverte | Ghosh, Tanay | CCSD

International audience. Over the course of cortical neurogenesis, the transition of progenitors from proliferation to differentiation requires a precise regulation of involved gene networks under varying environment...

Mi R ‐135b is a direct PAX 6 target and specifies human neuroectoderm by inhibiting TGF ‐β/ BMP signaling

Archive ouverte | Bhinge, Akshay | CCSD

International audience. Several transcription factors (TFs) have been implicated in neuroectoderm (NE) development, and recently, the TF PAX6 was shown to be critical for human NE specification. However, microRNA ne...

A Role for RE-1-Silencing Transcription Factor in Embryonic Stem Cells Cardiac Lineage Specification

Archive ouverte | Aksoy, Irene | CCSD

International audience. Abstract During development, lineage specification is controlled by several signaling pathways involving various transcription factors (TFs). Here, we studied the RE-1-silencing transcription...

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