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Prognostic Value of Trop-2 Expression in Nonmetastatic Triple-Negative Breast Cancer and Correlation With Emerging Biomarkers.

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Jacot, William | Chateau, Marie-Christine | Thezenas, Simon | Guiu, Séverine | Firmin, Nelly | Lafont, Virginie | Theillet, Charles | Boissière-Michot, Florence

Edité par CCSD ; Wiley -

International audience. Triple-Negative Breast Cancer (TNBC) is an aggressive breast cancer subtype, in which targeting the Trophoblast cell-surface antigen-2 (Trop-2), using antibody-drug conjugates (ADC), results in significant clinical improvement. However, clinicopathological correlations with Trop-2 protein expression levels remain limited in TNBC patients.

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