B regulatory cells in cancer

Archive ouverte

Balkwill, Frances | Montfort, Anne | Capasso, Melania

Edité par CCSD ; Elsevier -

International audience. B regulatory cells are a newly described subpopulation of B cells that appear to play important roles in autoimmunity and more recently, in cancer. In this review we summarize our current knowledge of B regulatory cells, as well as the body of evidence pointing towards a role for B cells in general, and B regulatory cells in particular, in promoting tumor growth.

Consulter en ligne

Suggestions

Du même auteur

Abstract 455: B cells actively participate to the anti-cancer immune response in high grade serous ovarian cancer metastases

Archive ouverte | Montfort, Anne | CCSD

International audience. Abstract Intra-tumor B cells and immunoglobulin signatures have been associated with a better clinical prognosis in ovarian cancer (Iglesia et al, 2014; Nielsen et al, 2012). However little i...

A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases

Archive ouverte | Montfort, Anne | CCSD

International audience. Purpose: In high-grade serous ovarian cancer (HGSOC), higher densities of both B cells and the CD8+ T-cell infiltrate were associated with a better prognosis. However, the precise role of B c...

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

Archive ouverte | Berlato, Chiara | CCSD

International audience. Elevated expression of the chemokine receptor CCR4 in tumors is associated with poor prognosis in several cancers. Here, we have determined that CCR4 was highly expressed in human renal cell ...

Chargement des enrichissements...