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RhoB Promotes γH2AX Dephosphorylation and DNA Double-Strand Break Repair

Archive ouverte | Mamouni, Kenza | CCSD

International audience

PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin

Archive ouverte | Mouly, Laetitia | CCSD

International audience. RHO GTPases regulate essential functions such as the organization of the actin cytoskeleton. The classic members cycle between an active GTP-bound and an inactive GDP-bound conformation where...

RhoB modifies estrogen responses in breast cancer cells by influencing expression of the estrogen receptor.

Archive ouverte | Médale-Giamarchi, Claire | CCSD

International audience. ABSTRACT: INTRODUCTION: RhoB has been reported to exert positive and negative effects on cancer pathophysiology but an understanding of its role in breast cancer remains incomplete. Analysis ...

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