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Spatial architecture of CD8 + T cells and DC subsets is critical for the response to immune checkpoint inhibitors in melanoma

Archive ouverte | Gobbini, Elisa | CCSD

Abstract Background Dendritic cells (DCs) are promising targets for cancer immunotherapies owing to their central role in the initiation and the control of immune responses. Their functions encompass a wide range of mechanisms med...

The spatial organization of cDC1 with CD8+ T cells is critical for the response to immune checkpoint inhibitors in melanoma patients

Archive ouverte | Gobbini, Elisa | CCSD

International audience. Abstract Dendritic cells (DCs) are promising targets for cancer immunotherapies because of their central role in the initiation and control of immune responses. The rare cDC1 population is of...

Identification of the dendritic cell landscape in human tumors by multi-immunofluorescence and scRNAseq

Archive ouverte | Hubert, Margaux | CCSD

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