Oncogenic Stress is a Novel Immunogenic Signal Driven by the Unfolded Protein Response and Detected by Neutrophils
Archive ouverte
| Debiesse, Antoine | CCSD
ABSTRACT Cellular transformation is initiated by a driver mutation, resulting in the abnormal expression of an oncogene or the loss of a tumor suppressor gene in a normal cell. This event leads to oncogenic stress (OS), describing...
A ganglioside-based immune checkpoint enables senescent cells to evade immunosurveillance during aging
Archive ouverte
| Iltis, Charlène | CCSD
International audience.
Although senescent cells can be eliminated by the immune system, they tend to accumulate with age in various tissues. Here we show that senescent cells can evade immune clearance by natural k...
The Multifaceted Neutrophils and Their Partners across Human Colorectal Cancer Road
