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Real-World Outcomes of Pralsetinib in RET Fusion-Positive NSCLC

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Lucibello, Francesca | Gounant, Valérie | Aldea, Mihaela | Duruisseaux, Michaël | Perol, Maurice | Chouaid, Christos | Bennouna, Jaafar | Fallet, Vincent | Renault, Aldo | Guisier, Florian | Giroux-Leprieur, Etienne | Wislez, Marie | Toffart, Anne-Claire | Mazieres, Julien | Basse, Clémence | Hegarat, Nadia | Carton, Matthieu | Girard, Nicolas

Edité par CCSD ; Elsevier -

International audience.

Introduction: Pralsetinib is a RET inhibitor found to have antitumor activity in advanced, metastatic, RET fusionpositive NSCLC.

Objective: To assess real-world efficacy of pralsetinib and treatment sequences in patients with RET fusion-positive NSCLC.

Design: Retrospective study of consecutive patients enrolled in the French expanded-access program for pralsetinib from December 1, 2019, to December 31, 2021.

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