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Ectodysplasin-A signaling is a key integrator in the lacrimal gland–cornea feedback loop

Archive ouverte | Kuony, Alison | CCSD

International audience. ABSTRACT A lack of ectodysplasin-A (Eda) signaling leads to dry eye symptoms, which have so far only been associated with altered Meibomian glands. Here, we used loss-of-function (Eda−/−) mut...

Hypolacrimia and Alacrimia as Diagnostic Features for Genetic or Congenital Conditions

Archive ouverte | Willems, Marjolaine | CCSD

International audience. As part of the lacrimal apparatus, the lacrimal gland participates in the maintenance of a healthy eye surface by producing the aqueous part of the tear film. Alacrimia and hypolacrimia, whic...

Bmi1+ Progenitor Cell Dynamics in Murine Cornea During Homeostasis and Wound Healing

Archive ouverte | Kalha, Solja | CCSD

International audience. Abstract The outermost layer of the eye, the cornea, is renewed continuously throughout life. Stem cells of the corneal epithelium reside in the limbus at the corneal periphery and ensure hom...

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