Evaluation of two modalities of perioperative treatment in the management of extremity and truncal soft tissue sarcomas: neoadjuvant concurrent chemoradiotherapy and sequential treatment

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Attal, J. | Cabarrou, B. | Valentin, T. | Nesseler, J. | Stoeckle, E. | Ducassou, A. | Filleron, T. | Le Guellec, S. | Boulet, B. | Vogin, G. | Ferron, G. | Moyal, E Cohen-Jonathan | Delannes, M. | Chevreau, C.

Edité par CCSD ; Springer Verlag (Germany) -

International audience. Patients with locally advanced grade 2-3 extremity/truncal soft tissue sarcomas (STS) are at high risk of recurrence. The objective of this study was to assess the efficacy and feasibility of neoadjuvant concurrent chemoradiotherapy (cCRT) in selected grade 2-3 patients with limb or trunk wall STS, and to compare this schedule to a sequential approach combining neoadjuvant chemotherapy and adjuvant radiotherapy.

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