Suggestions

Du même auteur

Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice

Archive ouverte | Soudais, Claire | CCSD

International audience. De novo synthesis of the pyrimidine, cytidine triphosphate (CTP), is crucial for DNA/RNA metabolism and depends on the CTP synthetases, CTPS1 and −2. Partial CTPS1 deficiency in humans has pr...

Molecular and functional characterization of the first human gain of function variant in LCK

Archive ouverte | Fusaro, Mathieu | CCSD

International audience

Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation

Archive ouverte | Minet, Norbert | CCSD

International audience. The CTP nucleotide is a key precursor of nucleic acids metabolism essential for DNA replication. De novo CTP production relies on CTP synthetases 1 and 2 (CTPS1 and CTPS2) that catalyze the c...

Chargement des enrichissements...