Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP C and Other Host-Specific Factors

0 avis

Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP C and Other Host-Specific Factors

Archive ouverte

Edité par CCSD ; American Society for Microbiology -

International audience. Prion propagation can be interfered with by the expression of a second prion protein in the host. In the present study, we investigated prion propagation in a host expressing two different prion protein genes.

Langue: en

Consulter en ligne

Consulter le document

Suggestions

Du même auteur

Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP C and Other Host-Specific Factors

Archive ouverte | Espinosa, Juan Carlos | CCSD

International audience. Early studies in transgenic mouse lines have shown that the coexpression of endogenous murine prion protein (PrPC) and transgenic PrPC from another species either inhibits or allows the propa...

Radical Change in Zoonotic Abilities of Atypical BSE Prion Strains as Evidenced by Crossing of Sheep Species Barrier in Transgenic Mice

Archive ouverte | Marín-Moreno, Alba | CCSD

International audience. Classical bovine spongiform encephalopathy (BSE) is the only zoonotic prion disease described to date. Although the zoonotic potential of atypical BSE prions have been partially studied, an e...

Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation

Archive ouverte | Espinosa, Juan Carlos | CCSD

Erratum in: JOURNAL OF INFECTIOUS DISEASES, 221(12): 2085-2085. DOI: 10.1093/infdis/jiaa073. Published: JUN 15 2020. Document Type: Correction. International audience. Although experimental transmission of bovine sp...

Chargement des enrichissements...