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Functional ultrasound imaging to study brain dynamics: Application of pharmaco-fUS to atomoxetine

Archive ouverte | Vidal, Benjamin | CCSD

International audience. Highlights• A first evaluation of the potential of fUS during a pharmacological challenge.• ATX modulates cerebral blood volume in areas associated with visual processing.• fUS as a new step ...

Pharmaco-fUS in cognitive impairment: Lessons from a preclinical model

Archive ouverte | Vidal, Benjamin | CCSD

International audience. Background: There is an urgent need to understand and reverse cognitive impairment. The lack of appropriate animal models combined with the limited knowledge of pathophysiological mechanisms ...

Pharmaco-fUS for Characterizing Drugs for Alzheimer’s Disease – The Case of THN201, a Drug Combination of Donepezil Plus Mefloquine

Archive ouverte | Vidal, Benjamin | CCSD

International audience. Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer’s disease (AD). Beyond the widely described neuronal impact of donepe...

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