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Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death. La sénescence cellulaire, nouvelle cible des infections virales respiratoires : du virus influenza au SARS-CoV-2

Archive ouverte | Sauve, Florent | CCSD

International audience. BackgroundWe have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during patholo...

Tanycytic networks mediate energy balance by feeding lactate to glucose-insensitive POMC neurons

Archive ouverte | Lhomme, Tori | CCSD

International audience. Hypothalamic glucose sensing enables an organism to match energy expenditure and food intake to circulating levels of glucose, the main energy source of the brain. Here, we established that t...

The hypothalamus as a hub for SARS-CoV-2 brain infection and pathogenesis

Archive ouverte | Nampoothiri, Sreekala | CCSD

Abstract Most patients with COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), display neurological symptoms, and respiratory failure in certain cases could be of extra-pulmonary origin. Hypothalamic...

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