A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo

Archive ouverte

Chiem, Kevin | Morales Vasquez, Desarey | Silvas, Jesus | Park, Jun-Gyu | Piepenbrink, Michael | Sourimant, Julien | Lin, Michelle | Greninger, Alexander | Plemper, Richard | Torrelles, Jordi | Walter, Mark | de la Torre, Juan | Kobie, James | Ye, Chengjin | Martinez-Sobrido, Luis

Edité par CCSD ; American Society for Microbiology -

International audience. SARS-CoV-2 is responsible of the COVID-19 pandemic that has warped daily routines and socioeconomics. There is still an urgent need for prophylactics and therapeutics to treat SARS-CoV-2 infections.

Consulter en ligne

Suggestions

Du même auteur

Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses

Archive ouverte | Ye, Chengjin | CCSD

International audience. Significance To date, due to the insufficient expression level of reporter genes from previous recombinant (r)SARS-CoV-2, in which the viral open reading frame (ORF) 7a gene was replaced by r...

Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice

Archive ouverte | Wong, Ting | CCSD

International audience. Emerging SARS-CoV-2 VoC are posing new problems regarding vaccine and monoclonal antibody efficacy. To better understand immune evasion tactics of the VoC, we utilized passive immunization to...

Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets

Archive ouverte | Cox, Robert | CCSD

International audience. Abstract Remdesivir is an antiviral approved for COVID-19 treatment, but its wider use is limited by intravenous delivery. An orally bioavailable remdesivir analog may boost therapeutic benef...

Chargement des enrichissements...