Trust in sources of information on COVID-19 at the beginning of the pandemic first wave and incident persistent symptoms: A prospective population-based cohort study

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Matta, J. | Wiernik, E. | Robineau, O. | Severi, G. | Touvier, M. | Gouraud, C. | Ouazana-Vedrines, C. | Pitron, V. | Ranque, B. | Hoertel, N. | van den Bergh, O. | Witthöft, M. | Kab, S. | Goldberg, M. | Zins, M. | Lemogne, C.

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International audience. BackgroundMany patients affected by COVID-19 suffer from persistent symptoms after infection. Compared to biomedical mechanisms, psychosocial mechanisms have been less investigated. This study examined the association between trust in sources of information on COVID-19 and the burden of incident persistent symptoms.MethodsA prospective study using data from the SAPRIS and SAPRIS-Sérologie surveys nested in the French CONSTANCES cohort. Trust in medical doctors, government, scientists, journalists, and social media was measured between April 2020 and May 2020. The number of incident persistent symptoms lasting for at least two months was recorded. Psychological burden was measured with the somatic symptom disorder B criteria scale. Associations between trust in information sources and outcomes were examined with zero-inflated negative binomial regression and general linear models, adjusting for gender, age, education, income, self-rated health, SARS-CoV-2 serology tests, and self-reported COVID-19ResultsAmong 20,985 participants, those with higher trust in government/journalists at baseline had fewer incident persistent symptoms at follow-up (estimate (SE): −0.21 (0.03), p < 0.001). Among 3372 participants (16.07%) who reported at least one symptom, those with higher trust in government/journalists and medical doctors/scientists had lower SSD-12 scores (−0.39 (0.17), p = 0.0219 and − 0.85 (0.24), p < 0.001, respectively), whereas higher trust in social media sources predicted higher SSD-12 scores in those with lower trust in government/journalists (0.90 (0.34), p = 0.008). These associations did not depend upon surrogate markers of past infection with SARS-CoV-2ConclusionTrust in information sources on COVID-19 should be tested as a target in the prevention of incident persistent symptoms.

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