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Molecular Pathways and Animal Models of Tetralogy of Fallot and Double Outlet Right Ventricle

Archive ouverte | Kelly, Robert, G | CCSD

International audience. Tetralogy of Fallot and Double outlet right ventricle are outflow tract (OFT) alignment defects situated on a continuous disease spectrum. A myriad of upstream causes can impact on ventriculo...

Cardiac Development and Animal Models of Congenital Heart Defects

Archive ouverte | Kelly, Robert, G | CCSD

International audience. The major events of cardiac development, including early heart formation, chamber morphogenesis and septation, as well as conduction system and coronary artery development, are briefly review...

The heart field transcriptional landscape at single-cell resolution

Archive ouverte | Kelly, Robert, G | CCSD

International audience. Organogenesis requires the orchestrated development of multiple cell lineages that converge, interact, and specialize to generate coherent functional structures, exemplified by transformation...

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