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Synthesis and pharmacological evaluation of dual ligands for melatonin (MT1/MT2) and serotonin 5-HT2C receptor subtypes (II)

Archive ouverte | Ettaoussi, Mohamed | CCSD

International audience. In this paper we report the investigation of C-3 and β-acetamide positions of agomelatine analogues. Concomitant insertion of a hydroxymethyl in the β-acetamide position and aliphatic groups ...

Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives

Archive ouverte | Landagaray, Elodie | CCSD

International audience. Following our research for new melatonergic ligands, herein we report the design, synthesis and biological evaluation of new series of naphthofuranic derivatives as MT1 and MT2 ligands. Bindi...

New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation

Archive ouverte | Landagaray, Elodie | CCSD

International audience

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