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Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

Archive ouverte | Cleynen, Isabelle | CCSD

International audience. Schizophrenia occurs in about one in four individuals with 22q11.2 deletion syndrome (22q11.2DS). The aim of this International Brain and Behavior 22q11.2DS Consortium (IBBC) study was to ide...

Parkinson's disease associated with 22q11.2 deletion: Clinical characteristics and response to treatment

Archive ouverte | Dufournet, Boris | CCSD

International audience. Background. - While it is known that 22q11.2 microdeletions (22q11.2-del) increase the risk of Parkinson's disease (PD), the characteristics of PD associated with 22q11.2-del have not been sp...

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Archive ouverte | Nalls, Mike | CCSD

International audience. Background: Genome-wide association studies (GWAS) in Parkinson's disease have increased the scope of biological knowledge about the disease over the past decade. We aimed to use the largest ...

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