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CtsR controls class III heat shock gene expression in the human pathogen Listeria monocytogenes

Archive ouverte | Nair, Shamila | CCSD

International audience. Stress proteins play an important role in virulence, yet little is known about the regulation of stress response in pathogens. In the facultative intracellular pathogen Listeria monocytogenes...

clpB, a novel member of the Listeria monocytogenes CtsR regulon, is involved in virulence but not in general stress tolerance

Archive ouverte | Chastanet, Arnaud | CCSD

International audience. Clp-HSP100 ATPases are a widespread family of ubiquitous proteins that occur in both prokaryotes and eukaryotes and play important roles in the folding of newly synthesized proteins and refol...

The CtsR regulator of stress response is active as a dimer and specifically degraded in vivo at 37 degrees C

Archive ouverte | Derré, Isabelle | CCSD

International audience. CtsR (class three stress gene repressor) negatively regulates the expression of class III heat shock genes (clpP, clpE and the clpC operon) by binding to a directly repeated heptanucleotide o...

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