Somatotopy of cervical dystonia in motor-cerebellar networks: Evidence from resting state fMRI

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Zito, Giuseppe, A | Tarrano, Clément | Jegatheesan, Prasanthi | Ekmen, Asya | Béranger, Benoît | Rebsamen, Michael | Hubsch, Cécile | Sangla, Sophie | Bonnet, Cécilia | Delorme, Cécile | Méneret, Aurélie | Degos, Bertrand | Bouquet, Floriane | Brissard, Marion Apoil | Vidailhet, Marie | Gallea, Cécile | Roze, Emmanuel | Worbe, Yulia

Edité par CCSD ; Elsevier -

International audience. Cervical dystonia is the most frequent form of isolated focal dystonia. It is often associated with a dysfunction in brain networks, mostly affecting the basal ganglia, the cerebellum, and the somatosensory cortex. However, it is unclear if such a dysfunction is somato-specific to the brain areas containing the representation of the affected body part, and may thereby account for the focal expression of cervical dystonia. In this study, we investigated resting state functional connectivity in the areas within the motor cortex and the cerebellum containing affected and non-affected body representations in cervical dystonia patients.

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