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Phenotyping polarization dynamics of immune cells using a lipid droplet-cell pairing microfluidic platform

Archive ouverte | Pinon, Léa | CCSD

International audience. The immune synapse is the tight contact zone between a lymphocyte and a cell presenting its cognate antigen. This structure serves as a signaling platform and entails a polarization of intrac...

Microtubules restrict F-actin polymerization to the immune synapse via GEF-H1 to maintain polarity in lymphocytes

Archive ouverte | Pineau, Judith | CCSD

International audience. Immune synapse formation is a key step for lymphocyte activation. In B lymphocytes, the immune synapse controls the production of high-affinity antibodies, thereby defining the efficiency of ...

Microtubules restrict F-actin polymerization to the immune synapse via GEF-H1 to maintain polarity in lymphocytes

Archive ouverte | Pineau, Judith | CCSD

International audience. Immune synapse formation is a key step for lymphocyte activation. In B lymphocytes, the immune synapse controls the production of high-affinity antibodies, thereby defining the efficiency of ...

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