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Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection.

Archive ouverte | Dharancy, Sébastien | CCSD

International audience. BACKGROUND AND AIMS: Liver inflammation, fibrosis, and dyslipidemia are common features in patients with chronic hepatitis C virus (HCV) infection. Because peroxisome proliferator-activated r...

micro-Opioid receptor activation prevents acute hepatic inflammation and cell death.

Archive ouverte | Chakass, Dania | CCSD

BACKGROUND AND AIMS: The detrimental impact of opioid agonist on the clinical management of inflammatory diseases remains elusive. Given the anti-inflammatory properties of the mu-opioid receptor (MOR) agonists at the intestinal b...

NOD2: a potential target for regulating liver injury.

Archive ouverte | Body-Malapel, Mathilde | CCSD

The recent discovery of bacterial receptors such as NOD2 that contribute to crosstalk between innate and adaptive immune systems in the digestive tract constitutes an important challenge in our understanding of liver injury mechan...

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