Obesity in adult patients with inflammatory bowel disease: Clinical features and impact on disability. A cross-sectional survey from the GETAID

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Bacha, Rose Al | Bouhnik, Yoram | Serrero, Melanie | Filippi, Jerome | Roblin, Xavier | Bourrier, Anne | Bouguen, Guillaume | Franchimont, Denis | Savoye, Guillaume | Buisson, Anthony | Louis, Edouard | Nancey, Stephane | Abitbol, Vered | Reimund, Jean-Marie | Dewit, Olivier | Vuitton, Lucine | Mathieu, Nicolas | Peyrin-Biroulet, Laurent | Gilletta, Cyrielle | Allez, Matthieu | Viennot, Stephanie | Berre, Catherine Le | Laharie, David | Nachury, Maria | Amiot, Aurelien | Tadbiri, Sara | Gagniere, Charlotte | Tannoury, Jenny | Pariente, Benjamin | Wils, Pauline | Stefanescu, Carmen | Treton, Xavier | Martins, Carole | Uzzan, Mathieu | Hébuterne, Xavier | Arab, Nadia | Cluzeau, Virginie | Tedesco, Emilie Del | Beaugerie, Laurent | Seksik, Philippe | Landmann, Cecilia | Kirchgesner, Julien | Sokol, Harry | Siproudhis, Laurent | Dewitte, Marie | Reenaers, Catherine | Boschetti, Gilles | Gay, Claire | Danion, Pauline | Flourié, Bernard | Malamut, Georgia | Caron, Benedicte | Dewitt, Olivier | Pestour, Sandie | Chateau, Thomas | Zallot, Camille | Gornet, Jean-Marc | Baudry, Clotilde | Bourreille, Arnaud | Trang-Poisson, Caroline | Dib, Nina | Brixi, Hedi | Cadiot, Guillaume | Boualit, Medina | Painchart, Claire | Plastaras, Laurianne | Altwegg, Romain | Boivineau, Lucile | Fumery, Mathurin | Caillo, Ludovic | Riviere, Pauline | Poullenot, Florian | Coffin, Benoit | Duboc, Henri | Nahon, Stephane | Tavernier, Noemie | Simon, Marion | Coulibaly, Baya | Amil, Morgane | Nicolas, Duveau | Khater, Sherine | Kaassis, Mehdi | Goutorbe, Felix | Moussata, Driffa | Picon, Laurence

Edité par CCSD ; Elsevier -

International audience. Background: In recent years, an increasing prevalence of obesity in inflammatory bowel disease (IBD) has been observed. However, only a few studies have focused on the impact of overweight and obesity on IBD-related disability.Aims: To identify the factors associated with obese and overweight patients with IBD, including IBD-related disability.Patients and methods: In this cross-sectional study, we included 1704 consecutive patients with IBD in 42 centres affiliated with the Groupe d'Etude Therapeutique des Affections Inflammatoires du tube Digestif (GETAID) using a 4-page questionnaire. Factors associated with obesity and overweight were assessed using univariate and multivariate analyses (odds ratios (ORs) are provided with 95% confidence intervals).Results: The prevalence rates of overweight and obesity were 24.1% and 12.2%, respectively. Multivariable analyses were stratified by age, sex, type of IBD, clinical remission and age at diagnosis of IBD. Overweight was significantly associated with male sex (OR = 0.52, 95% CI [0.39-0.68], p < 0.001), age (OR = 1.02, 95% CI [1.01-1.03], p < 0.001) and body image subscore (OR = 1.15, 95% CI [1.10-1.20], p < 0.001) (Table 2). Obesity was significantly associated with age (OR = 1.03, 95% CI [1.02-1.04], p < 0.001), joint pain subscore (OR = 1.08, 95% CI [1.02-1.14], p < 0.001) and body image subscore (OR = 1.25, 95% CI [1.19-1.32], p < 0.001) (Table 3).Conclusion: The increasing prevalence of overweight and obesity in patients with IBD is associated with age and poorer body image. A holistic approach to IBD patient care should be encouraged to improve IBD-related disability and to prevent rheumatological and cardiovascular complications.

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