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Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19

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Miltgen, Guillaume | Garrigos, Thomas | Cholley, Pascal | Deleume, Marine | Allou, Nicolas | Allyn, Jérôme | Wilkinson, David, A | Lugagne, Nathalie | Belmonte, Olivier | Bertrand, Xavier | Hocquet, Didier | Mavingui, Patrick

Edité par CCSD ; BioMed Central -

International audience. Concomitant prevention of SARS-CoV-2 and extensively drug-resistant bacteria transmission is a difficult challenge in intensive care units dedicated to COVID-19 patients. We report a nosocomial cluster of four patients carrying NDM-1 plasmid-encoded carbapenemase-producing Enterobacter cloacae. Two main factors may have contributed to crosstransmission: misuse of gloves and absence of change of personal protective equipment, in the context of COVID-19-associated shortage. This work highlights the importance of maintaining infection control measures to prevent CPE cross-transmission despite the difficult context and that this type of outbreak can potentially involve several species of Enterobacterales.

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