Suggestions

Du même auteur

Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates

Archive ouverte | Zwick, Vincent | CCSD

International audience. Conditions for the metathesis of alkenes in the convergent synthesis of HDAC inhibitors have been improved by continuous catalyst flow injection in the reaction media. Intermediate and target...

Selective molecular inhibition of the HDAC6 ZnF-UBP binding domain impairs multiple myeloma cell proliferation

Archive ouverte | Rincon, Rafael | CCSD

International audience. Multiple myeloma is a plasma cell malignancy with poor prognosis despite the recent development of new therapeutic options. Histone deacetylase 6 (HDAC6) is overexpressed in multiple myeloma ...

Bioactive metabolites from the leaves of Withania adpressa

Archive ouverte | Ben Bakrim, Widad | CCSD

International audience. Context:Withania (Solanaceae) species are known to be a rich source of withanolides, which have shown several biological properties.Objective: To identify the compounds responsible for Withan...

Chargement des enrichissements...