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Gene expression in regenerating liver in relation to cell proliferation and stress

Archive ouverte | Sobczak, Joelle | CCSD

International audience. When hepatocyte proliferation is stimulated in the liver by partial hepatectomy, messenger RNAs coding for fibrinogen, actin, c-myc and topoisomerase I are rapidly accumulated. We distinguish...

Comparison of biochemical properties of DNA-topoisomerase I from normal and regenerating liver

Archive ouverte | Tournier, Marie-Francoise | CCSD

International audience. Biochemical properties of topoisomerase I from normal and regenerating rat liver were analysed using crude or fractionated nuclear extracts. We could not detect significative change in topois...

Molecular cloning of mRNA sequences transiently induced during rat liver regeneration*1

Archive ouverte | Sobczak, Joelle | CCSD

International audience. In order to isolate genes which are induced during liver regeneration, we have constructed a cDNA library from 16-h-regenerating liver poly(A)+ RNA. By computer analysis of autoradiograms pro...

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