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Therapy Related Myeloid Neoplasms Following PARP Inhibitors: Real-Life Experience.

Archive ouverte | Marmouset, Vincent | CCSD

International audience. PURPOSE: To provide insights into the diagnosis and management of therapy-related myeloid neoplasms (t-MN) following PARP inhibitors (PARPi). EXPERIMENTAL DESIGN: In a French cancer center, w...

Therapy Related Myeloid Neoplasm Post PARP Inhibitors: Potential Clonal Selection.

Archive ouverte | Martin, Jean-Edouard | CCSD

International audience. Introduction Clonal selection is one of the mechanisms leading to therapy-related myeloid neoplasms (TRMN). A preexisting somatic mutation in hematopoietic stem cell (defined as clonal hemato...

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Archive ouverte | Vasseur, Loic | CCSD

Meeting abstract. International audience. Context. Measurable residual disease (MRD) is a major prognostic factor in Core Binding Factor (CBF) AML (Jourdan et al. 2014, Döhner et al., 2022). Recurrent genetic altera...

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