Suggestions

Du même auteur

Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof

Archive ouverte | Suhy, David | CCSD

Established PABPN1 intranuclear inclusions in OPMD muscle can be efficiently reversed by AAV-mediated knockdown and replacement of mutant expanded PABPN1

Archive ouverte | Malerba, Alberto | CCSD

International audience

Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing

Archive ouverte | Klein, Pierre | CCSD

International audience. A short abnormal polyalanine expansion in the polyadenylate-binding protein nuclear-1 (PABPN1) protein causes oculopharyngeal muscular dystro-phy (OPMD). Mutated PABPN1 proteins accumulate as...

Chargement des enrichissements...