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Monocyte NOTCH2 expression predicts IFN-β immunogenicity in multiple sclerosis patients

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Adriani, Marsilio | Nytrova, Petra | Mbogning, Cyprien | Hässler, Signe | Medek, Karel | Jensen, Poul Erik H. | Creeke, Paul | Warnke, Clemens | Ingenhoven, Kathleen | Hemmer, Bernhard | Sievers, Claudia | Lindberg Gasser, Raija L.P. | Fissolo, Nicolas | Deisenhammer, Florian | Bocskei, Zsolt | Mikol, Vincent | Fogdell-Hahn, Anna | Kubala Havrdova, Eva | Broët, Philippe | Dönnes, Pierre | Mauri, Claudia | Jury, Elizabeth, C

Edité par CCSD ; American Society for Clinical Investigation -

International audience. , and Genentech; he has served as DMSC member for AllergyCare; he or his institution have received speaker honoraria from Biogen Idec, Teva Neuroscience, Merck Serono, Medimmune, Novartis, Desitin, and F. Hoffmann-La Roche Ltd.; his institution has received research support from Chugai Pharmaceuticals and Hoffmann-La-Roche; he holds part of 2 patents-1 for the detection of antibodies and T cells against KIR4.1 in a subpopulation of MS patients and 1 for genetic determinants of neutralizing antibodies to interferon β. EKH has received honoraria/research support from Actelion, Biogen, Czech Ministry of Education project PROGRES Q27/LF1,

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