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Les anticorps anti-biomédicament sont négativement associés à la réponse au traitement par anti-TNF monoclonaux et anti-IL-6 récepteur dans la polyarthrite rhumatoïde : les résultats de l'étude ABIRISK

Archive ouverte | Bitoun, Samuel | CCSD

International audience

Methotrexate and BAFF interaction prevents immunization against TNF inhibitors

Archive ouverte | Bitoun, Samuel | CCSD

International audience. Objectives TNF inhibitors (TNFi) can induce anti-drug antibodies (ADA) in patients with autoimmune diseases (AID) leading to clinical resistance. We explored a new way of using methotrexate (...

Long-term exposure to monoclonal anti-TNF is associated with an increased risk of lymphoma in BAFF-transgenic mice

Archive ouverte | Nocturne, Gaetane | CCSD

International audience. Summary The impact of treatment on the risk of lymphoma in patients with rheumatoid arthritis (RA) is unclear. Here, we aimed to assess if the risk of lymphoma differs according to the type o...

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