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Area under the curve of tacrolimus using microsampling devices: towards precision medicine in solid organ transplantation?

Archive ouverte | Couette, Aurélien | CCSD

International audience. Purpose - Therapeutic drug monitoring of tacrolimus using trough concentration (C) is mandatory to ensure drug efficacy and safety in solid organ transplantation. However, C is just a proxy f...

Tacrolimus overexposure in kidney transplant recipients during the first post-operative week: caution is required in older patients

Archive ouverte | Lemaitre, Florian | CCSD

International audience. In liver transplantation, tacrolimus trough concentrations (Cmin) above 20 ng/mL during the first days led to worse outcome at 1 year but data in the kidney transplant (KT) era are scarce. Th...

Comparison of different equations for renal function evaluation as proxies for antibiotic drug clearance: the examples of amoxicillin and cloxacillin

Archive ouverte | Duval, Xavier | CCSD

International audience. The most appropriate renal function estimation equation to predict drug clearance is a matter of debate. In this study, we compare the Modification of Diet in Renal Disease (MDRD), the Chroni...

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