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Extrinsic apoptosis participates to tail regression during the metamorphosis of the chordate Ciona

Archive ouverte | Krasovec, Gabriel | CCSD

International audience. Apoptosis is a regulated cell death ubiquitous in animals defined by morphological features depending on caspases. Two regulation pathways are described, currently named the intrinsic and the...

Comparative transcriptomic analysis reveals gene regulation mediated by caspase activity in a chordate organism

Archive ouverte | Krasovec, Gabriel | CCSD

International audience. Background: Apoptosis is a caspase regulated cell death present in all metazoans defined by a conserved set of morphological features. A well-described function of apoptosis is the removal of...

Intrinsic apoptosis is evolutionarily divergent among metazoans

Archive ouverte | Krasovec, Gabriel | CCSD

International audience. Apoptosis is regulated cell death that depends on caspases. A specific initiator caspase is involved upstream of each apoptotic signaling pathway. Characterized in nematode, fly, and mammals,...

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