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MT5-MMP is a modulator of inflammation: a study in murine and human neural cells related to Alzheimer’s disease

Archive ouverte | Pilat, Dominika | CCSD

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Human iPSCs-derived astrocytes reveal APOE as a critical modulator of inflammation that could underlie Alzheimer’s disease pathogenesis

Archive ouverte | Arnaud, Laurie | CCSD

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MT5-MMP controls APP and β-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer’s disease

Archive ouverte | García-González, Laura | CCSD

We previously discovered the implication of membrane-type 5-matrix metalloproteinase (MT5-MMP) in Alzheimer’s disease AD pathogenesis. Here we shed new light on pathogenic mechanisms by which MT5-MMP controls APP processing and th...

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