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Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis

Archive ouverte | Lenoir, Olivia | CCSD

International audience. The glomerulus is a highly specialized capillary tuft, which under pressure filters large amounts of water and small solutes into the urinary space, while retaining albumin and large proteins...

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Archive ouverte | Henique, Carole | CCSD

International audience. Crescentic rapidly progressive glomerulonephritis (RPGN) represents the most aggressive form of acquired glomerular disease. While most therapeutic approaches involve potentially toxic immuno...

Calpastatin prevents Angiotensin II–mediated podocyte injury through maintenance of autophagy

Archive ouverte | Bensaada, Imane | CCSD

International audience. The strong predictive value of proteinuria in chronic glomerulopathies is firmly established as well as the pathogenic role of angiotensin II promoting progression of glomerular disease with ...

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