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A novel role for myeloid endothelin-B receptors in hypertension

Archive ouverte | Czopek, Alicja | CCSD

International audience

A novel role for myeloid endothelin-B receptors in hypertension

Archive ouverte | Czopek, Alicja | CCSD

International audience. AIMS:Hypertension is common. Recent data suggest that macrophages (Mφ) contribute to, and protect from, hypertension. Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor with ad...

Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

Archive ouverte | Guyonnet, Léa | CCSD

International audience. The endothelin system may be an important player in hypertensive end-organ injury as endothelin-1 increases blood pressure and is pro-inflammatory. The immune system is emerging as an importa...

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