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Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation

Archive ouverte | Calon, A | CCSD

International audience. Aims: The CDX1 and CDX2 homeoproteins are intestine-specific transcription factors regulating homeostasis. We investigated their relevance in experimentally-induced intestinal inflammation.Me...

The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development

Archive ouverte | Bonhomme, C | CCSD

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The Microenvironment Controls CDX2 Homeobox Gene Expression in Colorectal Cancer Cells

Archive ouverte | Benahmed, Fairouz | CCSD

International audience. The homeobox gene CDX2 plays a major role in development, especially in the gut, and it also acts as a tumor suppressor in the adult colon. Using orthotopic and heterotopic xenografts of huma...

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