Suggestions

Du même auteur

The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains

Archive ouverte | Di Cesare, Margot | CCSD

International audience. ATP-binding cassette (ABC) transporters are ubiquitous membrane proteins responsible for the translocation of a wide diversity of substrates across biological membranes. Some of them confer m...

Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter

Archive ouverte | Chaptal, Vincent | CCSD

International audience. Multidrug ABC transporters translocate drugs across membranes by a mechanism for which the molecular features of drug release are so far unknown. Here, we resolved three ATP-Mg$^{2+}$–bound o...

Structural insights into the semiquinone form of human Cytochrome P450 reductase by DEER distance measurements between a native flavin and a spin labelled non‐canonical amino acid

Archive ouverte | Bizet, Maxime | CCSD

International audience. The flavoprotein Cytochrome P450 reductase (CPR) is the unique electron pathway from NADPH to Cytochrome P450 (CYPs). The conformational dynamics of human CPR in solution, which involves tran...

Chargement des enrichissements...