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Comparison of performance between three SARS‐CoV‐2 molecular assays (Aptima™, Laboratory Developed Test‐Fusion, and R‐GENE®) with special attention to turnaround time, a key point in laboratory management

Archive ouverte | Lefeuvre, Caroline | CCSD

International audience. Abstract The emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) highlights the importance of rapid diagnostic testing to identify individuals with SARS‐CoV‐2 infections...

Natural non-homologous recombination led to the emergence of a duplicated V3-NS5A region in HCV-1b strains associated with hepatocellular carcinoma

Archive ouverte | Le Guillou-Guillemette, Hélène | CCSD

International audience. Background: The emergence of new strains in RNA viruses is mainly due to mutations or intra and inter-genotype homologous recombination. Non-homologous recombinations may be deleterious and a...

Analysis of hepatic fibrosis markers in the serum of chronic hepatitis B patients according to basal core promoter/precore mutants

Archive ouverte | Lefeuvre, Caroline | CCSD

International audience. The A1762T/G1764A double mutant in the basal core promoter (BCP) region of the hepatitis B virus (HBV) is associated with severe hepatic lesions while the G1899A mutation with the double muta...

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