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Cosson, Emmanuel | Bentounes, Sid Ahmed | Nachtergaele, Charlotte | Berkane, Narimane | Pinto, Sara | Sal, Meriem | Bihan, Hélène | Tatulashvili, Sopio | Portal, Jean-Jacques | Carbillon, Lionel | Vicaut, Eric | Gräsner, Jan-Thorsten | Lefering, Rolf | Koster, Rudolph | Masterson, Siobhán | Böttiger, Bernd | Herlitz, Johan | Wnent, Jan | Tjelmeland, Ingvild B.M. | Ortiz, Fernando Rosell | Maurer, Holger | Baubin, Michael | Mols, Pierre | Hadžibegoviŀ, Irzal | Ioannides, Marios | Škulec, Roman | Wissenberg, Mads | Salo, Ari | Hubert, Hervé | Nikolaou, Nikolaos | Lóczi, Gerda | Svavarsdóttir, Hildigunnur | Semeraro, Federico | Wright, Peter | Clarens, Carlo | Pijls, Ruud | Cebula, Grzegorz | Correia, Vitor Gouveia | Cimpoesu, Diana | Raffay, Violetta | Trenkler, Stefan | Markota, Andrej | Strömsöe, Anneli | Burkart, Roman | Perkins, Gavin | Bossaert, Leo | Kaufmann, Marc | Thaler, Markus | Maier, Martin | Prause, Gerhard | Trimmel, Helmut | de Longueville, Diane | Preseau, Thierry | Biarent, Dominique | Melot, Christian | Mpotos, Nicolas | Monsieurs, Koen | van de Voorde, Patrick | Vanhove, Marie | Lievens, Pascale | Faniel, Mathias | Keleuva, Slobodanka | Lazarevic, Milan | Ujevic, Radmila Majhen | Devcic, Mato | Bardak, Branka | Barisic, Fabijan | Anticevic, Silvija Hunyadi | Georgiou, Marios | Truhlás, Anatolij | Knor, Jisí | Smržová, Eva | Sviták, Roman | Šín, Robin | Mokrejš, Petr | Lippert, Freddy | Hallikainen, Juhana | Hoikka, Marko | Iirola, Timo | Jama, Timo | Jäntti, Helena | Jokisalo, Raimo | Jousi, Milla | Kirves, Hetti | Kuisma, Markku | Laine, Jukka | Länkimäki, Sami | Loikas, Petri | Lund, Vesa | Määttä, Teuvo | Nal, Heini | Niemelä, Heimo | Portaankorva, Petra | Pylkkänen, Marko | Sainio, Marko | Setälä, Piritta | Tervo, Jerry | Väyrynen, Taneli | Murgue, Davy | Champenois, Anne | Fournier, Marc | Meyran, Daniel | Tabary, Romain | Avondo, Aurélie | Gelin, Gelin | Simonnet, Bruno | Joly, Marc | Megy-Michoux, Isabelle | Paringaux, Xavier | Duffait, Yves | Vial, Michael | Segard, Julien | Narcisse, Sophie | Hamban, David | Hennache, Jonathan | Thiriez, Sylvain | Doukhan, Mathieu | Vanderstraeten, Carine | Morel, Jean-Charles | Majour, Gilles | Michenet, Corinne | Tritsch, Laurent | Dubesset, Marc | Peguet, Olivier | Pinero, David | Guillaumee, Fréderic | Fuster, Patrick | Ciacala, Jean-François | Jardel, Benoît | Letarnec, Jean-Yves | Goes, Frank | Gosset, Pierre | Vergne, Muriel | Bar, Christian | Branche, Fabienne | Prineau, Stevens | Lagadec, Steven | Cornaglia, Carole | Ursat, Cécile | Agostinucci, Jean-Marc | Nadiras, Pierre | de Linares, Géraldine Gonzales | Jacob, Line | Revaux, François | Pernot, Thomas | Roudiak, Nathalie | Ricard-Hibon, Agnès | Villain-Coquet, Laurent | Beckers, Stefan | Hanff, Thomas | Strickmann, Bernd | Wiegand, Nicolai | Wilke, Petra | Sues, Harald | Bogatzki, Stefan | Baumeier, Wolfgang | Pohl, Kai | Werner, Bert | Fischer, Hans | Zeng, Torsten | Popp, Erik | Günther, Andreas | Hochberg, Andreas | Lechleuthner, Alex | Schewe, Jens-Christian | Lemke, Hans | Wranze-Bielefeld, Erich | Bohn, Andreas | Roessler, Markus | Naujoks, Frank | Sensen, Frank | Esser, Torben | Fischer, Matthias | Messelken, Martin | Rose, Christopher | Schlüter, Gabriele | Lotz, Wolfgang | Corzilius, Michael | Muth, Claus-Martin | Diepenseifen, Christian | Tauchmann, Björn | Birkholz, Torsten | Flemming, Andreas | Herrmann, Stefanie | Kreimeier, Uwe | Kill, Clemens | Marx, Frank | Schröder, Ralph | Lenz, Wolfgang | Botini, Glykeria | Grigorios, Barakos | Giannakoudakis, Nikolaos | Zervopoulos, Michail | Papangelis, Dimitrios | Petropoulou-Papanastasiou, Sofia | Liaskos, Themistoklis | Papanikolaou, Spyridon | Karabinis, Andreas | Zentay, Attila | Ÿorsteinsson, Hólmgeir | Gilsdóttir, Anna | Birgisson, Svavar | Guðmundsson, Fjölnir Freyr | Hreiðarsson, Hallgrímur | Ÿrnason, Björgvin | Hermannsson, Hermann | Björnsson, Gísli | Friðriksson, Brynjar Ÿór | Baldursson, Gunnar | Höskuldsson, Ÿrmann | Valgarðsdottir, Jórunn | Ÿsmundardóttir, Matthildur | Guðmundsson, Guðmundur | Kristjánsson, Hjörtur | Ÿórarinsson, Eyþór Rúnar | Guðlaugsson, Jón | Skarphéðinsson, Sigurður | Peratoner, Alberto | Santarelli, Andrea | Sabetta, Cesare | Gordini, Giovanni | Sesana, Giovanni | Giudici, Riccardo | Savastano, Simone | Pellis, Tommaso | Beissel, Jean | Uhrig, Jean | Manderscheid, Tom | Klop, Marco | Stammet, Pascal | Koch, Marc | Welter, Philippe | Schuman, Robert | Bruins, Wendy | Amin, Hesam | Braa, Nina | Bratland, Staale | Buanes, Eirik Alnes | Draegni, Tomas | Johnsen, Knut Roar | Mathisen, Wenche Torunn | Oedegaarden, Terje | Oppedal, Marie | Reksten, Alf Stolt-Nielsen | Roedsand, Mats Eirik | Steen-Hansen, Jon Erik | Dyrda, Marta | Frejlich, Anna | Maciŀg, Ssawomir | Osadnik, Sonia | Weryk, Ireneusz | Mendonça, Eugénio | Freitas, Carlos | Cruz, Pinto | Caldeira, Carmo | Barros, José | Vale, Luis | Brazão, António | Jardim, Nuno | Rocha, Fernanda | Duarte, Ricardo | Fernandes, Nicodemos | Ramos, Pedro | Jardim, Margarida | Reis, Miguel | Ribeiro, Romulo | Zenha, Sérgio | Fernandes, Jorge | Francisco, Juan | Assis, David | Abreu, Fernanda | Freitas, Dinarte | Ribeiro, Leonardo | Azevedo, Paulo | Calafatinho, Débora | Jardim, Rui | Pestana, Aleixo | Faria, Rui | Oprita, Bogdan | Grasu, Alis | Nedelea, Paul | Sovar, Sorina | Agapi, Florin | Kliŀkoviŀ, Aleksandar | Laziŀ, Aleksandra | Nikoliŀ, Bogdan | Zivanovic, Bogdan | Martinoviŀ, Branislav | Milenkoviŀ, Dušan | Damir, Huseinoviŀ | Koprivica, Jovanka | Jakšiŀ, Kornelija Horvat | Pajor, Margit | Miliŀ, Saša | Vidoviŀ, Mirko | Glamoclija, Radojka Petrovic | Andjelic, Sladjana | Sladjana, Vlajovic | Babiŀ, Zlatko | Fišer, Zlatko | Androvic, Peter | Bajerovska, Lubica | Chabron, Miroslav | Dobias, Viliam | Havlikova, Eva | Horanova, Bozena | Kratochvilova, Renata | Kubova, Dana | Murgas, Jan | Patras, Juraj | Simak, Ladislav | Snarskij, Vladimir | Zaviaticova, Zuzana | Zuffova, Marcela | Roig, Francesc Escalada | Santos, Luis Sánchez | Sucunza, Alfredo Echarri | Cordero Torres, Juan | Muñoz, Guadalupe Inza | del Valle, Marta Martínez | Rozalen, Isabel Ceniceros | Sánchez, Enrique Martín | Berlanga, María Victoria Raúl Canabal | Olalde, Karlos Ibarguren | Ruiz Azpiazu, José | García-Ochoa, María José | López-Navarro, Rafael Zoyo | Adsuar Quesada, José | Cortés Ramas, José | Mellado Vergel, Francisco | López Messa, Juan | del Valle, Patricia Fernández | Anselmi, Luciano | Benvenuti, Breganzona Claudio | Batey, Nigel | Ambulance, Yorkshire | Booth, Scott | Bucher, Patricia | Deakin, Charles | Duckett, Jay | Ji, Chen | Loughlin, Nancy | Lumley-Holmes, Jenny | Lynde, Jessica | Mersom, Frank | Ramsey, Carly | Robinson, Clare | Spaight, Robert | Dosanjh, Sukhdeep | Virdi, Gurkamal | Whittington, Andrew
Edité par
CCSD ; Elsevier -
International audience.
We aimed to compare pregnancy outcomes in 4665 women according to the following types of hyperglycaemia in pregnancy sub-types: (i) normoglycaemia, (ii) gestational diabetes mellitus (GDM), (iii) diabetes in pregnancy (DIP), (iv) early-diagnosed (i.e., <22 weeks of gestation) GDM (eGDM), and (v) early-diagnosed DIP (eDIP). The prevalence of normoglycaemia, eGDM, eDIP, GDM, and DIP was 76.4%, 10.8%, 0.6%, 11.7%, and 0.6%, respectively. With regard to pregnancy outcomes, gestational weight gain (11.5 ± 5.5, 9.0 ± 5.4, 8.3 ± 4.7, 10.4 ± 5.3, and 10.1 ± 5.0 kg, p < 0.0001) and insulin requirement (none, 46.0%, 88.5%, 25.5%, and 51.7%; p < 0.001) differed according to the glycaemic sub-types. eGDM and eDIP were associated with higher rates of infant malformation. After adjustment for confounders, with normoglycaemia as the reference, only GDM was associated with large-for-gestational-age infant (odds ratio 1.34 (95% interval confidence 1.01–1.78) and only DIP was associated with hypertensive disorders (OR 3.48 (1.26–9.57)). To conclude, early-diagnosed hyperglycaemia was associated with an increased risk of malformation, suggesting that it was sometimes present at conception. Women with GDM, but not those with eGDM, had an increased risk of having a large-for-gestational-age infant, possibly because those with eGDM were treated early and therefore had less gestational weight gain. Women with DIP might benefit from specific surveillance for hypertensive disorders.
