TFIIH contains a PH domain involved in DNA nucleotide excision repair

Archive ouverte | Gervais, Virginie | CCSD

International audience. The human general transcription factor TFIIH is involved in both transcription and DNA repair. We have identified a structural domain in the core subunit of TFIIH, p62, which is absolutely re...

Structural Characterization of the Cysteine-rich Domain of TFIIH p44 Subunit

Archive ouverte | Fribourg, Sébastien | CCSD

Solution structure of the C-terminal domain of TFIIH P44 subunit reveals a novel type of C4C4 ring domain involved in protein-protein interactions.

Archive ouverte | Kellenberger, Esther | CCSD

International audience. The human general transcription factor TFIIH is involved in both transcription and DNA nucleotide excision repair. Among the 10 subunits of the complex, p44 subunit plays a crucial role in bo...