FP09.05 Driver Oncogenic Alterations and Indoor Radon in NSCLC Patients From the IFCT Biomarker Cohort: Bioradon France Study

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Mezquita, L. | Barlesi, F. | Ielsch, G. | Merlio, J. | Debieuvre, D. | Mosser, J. | Ricordel, C. | Ouafik, L'Houcine | Rouquette, I. | Monnet, I. | Escande, F. | Langlais, A. | Morin, F. | Vignaud, C. | Auclin, E. | Benitez, J.C. | Planchard, D. | Leuraud, K. | Laurier, D. | Besse, B. | Westeel, V.

Edité par CCSD ; Lippincott, Williams & Wilkins -

International audience. Those with FH of LC were more likely to be obese regardless of demographic factors, and less likely to exercise 2+ times per week (Table). Those with FH of LC were more likely to have received 10+ imaging scans and to have been exposed to hydrocarbons compared to those without FH (Table). There were no reported differences in any other occupational or home exposures, including asbestos and radon in those with v. without FH of LC (Table). Conclusion: FH of LC is associated with higher-risk behaviors that increase the likelihood of developing both lung and other cancers. As such, FH can be used in cancer prevention and control programs to identify higher-risk patients and educate patients that FH of lung cancer is associated with risk-increasing behaviors that are nonetheless modifiable.

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